Be Cautious In Giving Pain Killer To Patients With High Cholesterol



Posted: Thursday, September 29, 2011

by Dr K K Aggarwal
Heart Care Foundation of India

One should not give long term non-steroidal anti-inflammatory pain killer drugs such as naproxen to patients with high cholesterol said Padmashri and Dr B C Roy national Awardee Dr K K Aggarwal President Heart Care Foundation of India and MTNL Perfect Health Mela.

In a swine model study published in Surgery Dr Frank Sellke, chief of cardiothoracic surgery and research at Rhode Island Hospital found that a high-cholesterol diet reduced blood flow to the heart muscle in animal models with chronic heart disease when given daily naproxen. They also found reduced levels of prostacyclin, a compound that dilates blood vessels and prevents blood clots.

These findings suggest that there may be a stronger risk of negative effects on the heart in patients who have high cholesterol levels and are taking NSAIDs as a form of pain or inflammation relief."

About the author: Padmashri & Dr. B.C. Roy National Awardee, Dr. KK Aggarwal is a Senior Consultant, Physician, Cardiologist at Delhi based Moolchand Medcity; President Heart Care Foundation of India; Chairman Ethical Committee Delhi Medical Council and has served as the Research and Academic Wing Heads of National Indian Medical Association
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